Endocrine Abstracts

We report the case of a 73-year-old Cypriot man with bilateral adrenal histoplasmosis. He had spent many years working in Southern Africa and had retired to Cyprus more than ten years ago. One year prior to diagnosis he underwent an elective cholecystectomy. Pre-operatively bilateral adrenal co-incidentalomas were noted on ultrasound and computed tomography (CT). Fine needle aspiration showed adipocytes within the gland and the patient had no further investigations at this tim...

A 22-year-old lady presented with an acute abdomen and underwent appendicectomy for early appendicitis. Post-operatively she developed headache, dizziness and neck stiffness, and later impaired attention and perseveration. Clinical examination showed papilloedema, a left IVth nerve palsy and left sided cerebellar signs. A CT head scan showed evidence of subarachnoid haemorrhage (SAH) and subsequent MRI confirmed SAH with some meningeal enhancement, as well as intraparenchymal ...

Objective: Cinacalcet, a calcimimetic that reduces parathyroid hormone (PTH) secretion and serum calcium (S-Ca) levels by increasing the sensitivity of calcium-sensing receptors has been introduced for the treatment of patients with persistent or recurrent primary hyperparathyroidism (PHPT). Within a prospective, non-interventional cohort study we identified patients with newly diagnosed PHPT who have been started on cinacalcet. Patient characteristics, treatment indications a...

Objective: Evaluate cinacalcet use and effect based on follow-up within a cohort study of recently diagnosed Primary Hyperparathyroidism (PHPT) patients. Characteristics, treatment indications and biochemical data are presented with measures of cinacalcet efficacy and safety.Methods: The Swiss Primary Hyperparathyroidism Cohort Study is a prospective, non-interventional project to collect clinical, biochemical and outcome data in patients with PHPT initi...